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  • 產(chǎn)品名稱：Eplerenone

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Eplerenone
詳情介紹：
Purpose Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. Eplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors.
Characteristics Tradename: Inspra
Source of Compound: synthetic
Target: Mineralocorticoid Receptor Antagonist LIPT1 Multivitamin uptake inhibitor,VB
Receptor: Mineralocorticoid Receptor
Status: USP
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C24H30O6
Solubility DMSO <1 mg="" ml,="" water="" <1="" ml="" <="" td="">
Molecular Weight 414.49 g/mol
CAS-No 107724-20-9
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months