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  • 產(chǎn)品名稱(chēng)：NK3Homeobox1(NKX3-1)(MiddleRegion)Peptide

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簡(jiǎn)單介紹：
NK3Homeobox1(NKX3-1)(MiddleRegion)Peptide
詳情介紹：
Blocked Antibody anti-NK3 Homeobox 1 (NKX3-1) (Middle Region) antibody (ABIN2779964)
Sequence TPTEPESDAH FETYLLDCEH NPGDLASAPQ VTKQPQKRSR AAFSHTQVIE
Characteristics This is a synthetic peptide designed for use in combination with anti-Nkx3-1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.

Alias Symbols: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe

Protein Size: 237
Molecular Weight 27 kDa
Gene ID 18095
NCBI Accession NM_010921, NP_035051
UniProt P97436
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.